Explainer
Evidence-led entry points for non-clinicians. What is a GLP-1 receptor agonist, what does ATC A10BX mean, why are some peptides legal in Russia but not the EU.
NVAC charter, GLP-1 telehealth: July 2026
NVAC gets a new charter on 7 July 2026, LifeMD faces GLP-1 telehealth allegations, and Medicare proposes 19% more pay for tobacco counselling.
TTT1: triple therapy for type 1 diabetes
The TTT1 Phase 3 trial tests semaglutide and dapagliflozin added to insulin in overweight adults with type 1 diabetes and poor glycaemic control.
Surgery vs semaglutide: Reddit concerns
NLP of 45,972 Reddit comments: surgery patients cite pain; semaglutide users cite GI and psychological effects. Pre-op anxiety runs 4x higher than post-op.
Semax and Selank: normal, N-Acetyl, Amidate
N-Acetyl and Amidate caps extend peptide half-life by blocking degradation, not by changing the receptor mechanism. Here is the biochemistry.
LifeMD GLP-1 safety claims and Iowa's PBM
Former LifeMD employees allege GLP-1 prescriptions were rushed. An Iowa audit found a PBM may have overcharged Medicaid by over $100 million.
BPC-157 and TB-500 while on a GLP-1 agonist
No published study has examined BPC-157 or TB-500 combined with a GLP-1 agonist. Both are unapproved drugs; the interaction picture is unknown.
Cagrilinitide without a GLP-1: the evidence
Cagrilinitide is an amylin analogue. Phase 2 data show 8.1% weight loss as monotherapy, but GI side effects run similar to semaglutide.
GHK-Cu injection nodule: what to know
A firm, painless lump at a GHK-Cu injection site lasting two weeks is usually a sterile tissue reaction. Here is what drives it and when to see a clinician.
PAD and GLP-1 drugs: the 2026 evidence
A 2026 European Heart Journal review names semaglutide as the only anti-obesity drug shown to cut cardiovascular events in high-risk patients without diabetes.
Semaglutide TBI study: blood-brain barrier
A 2026 mouse study found semaglutide promoted angiogenesis and blood-brain barrier repair after traumatic brain injury via a PDGF-BB/PDGFRbeta/VEGF cascade.
Wolverine stack for shoulder and elbow pain
BPC-157 and TB-500 have animal data on tendon healing but no human trials for shoulder or elbow injury. Here is what the research actually shows.
Bariatric surgery volumes fell 39%
Epic Cosmos data show US bariatric surgery peaked in Q4 2022 and fell 39% by Q4 2025. Access to GLP-1 agonists before surgery splits sharply by insurance.