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Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.

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Explainer

GLP-1 gastroparesis symptoms and the gaps

A 2026 systematic review found only 12 published case reports of GLP-1 gastroparesis. Here is what they showed, and what they cannot tell you.

14 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 drugs at longevity clinics

Longevity and aesthetic clinics prescribe semaglutide and tirzepatide off-label. Here is what the labels cover, and where the ageing evidence stops.

14 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

SS-31, MOTS-c, and Tesamorelin: Evidence

What the published research says about SS-31, MOTS-c, GHK-Cu, and tesamorelin when people consider adding them to a retatrutide regimen.

14 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Peptide cycles per year: no number exists

Cycle lengths come from a few small trials. Cycle counts come from nowhere, because no study has tested repeating a peptide course across a year.

14 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

Tirzepatide, blood pressure, cholesterol

A SURMOUNT post hoc analysis scores tirzepatide on all three targets at once. Between 32% and 38% of participants hit every one. Composites read differently.

14 Aug 2026 · PeptideMethods Editorial Team · 6 min read
Explainer

Traveling to UK with Peptides: The Rules

UK law sets clear documentation rules for controlled drugs like TRT, while CJC-1295 and ipamorelin sit in a separate, less defined space.

14 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 agonists: laryngeal side effects

A 2026 study found GLP-1 receptor agonists raised cough and voice disorder risk in obese adults.

13 Aug 2026 · PeptideMethods Editorial Team · 3 min read
Explainer

Beyond weight loss: GLP-1 organ outcomes

A JACC editorial reframes GLP-1 drugs as cardiometabolic medicines. The SELECT, FLOW and SOUL trials, and the approved labels, already point that way.

13 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Do GLP-1 drugs cause throat symptoms?

A 2026 Laryngoscope cohort ties GLP-1 drugs to cough, globus and voice change. Here is what an association study can and cannot show.

13 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 drugs as cardiometabolic medicines

A 2026 JACC editorial argues GLP-1 drugs are cardiometabolic medicines first. Here is what the trial evidence shows.

13 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

What Lilly's retatrutide lawsuits mean

Eli Lilly sued six US sellers of unapproved retatrutide on 12 August 2026. Here is what the cases mean if you bought a vial or are considering one.

13 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Obesity-driven HFpEF: what the drugs do

A 2026 review maps obesity-driven HFpEF from mechanism to prescribing. Semaglutide and tirzepatide improved symptoms and exercise capacity, not survival.

13 Aug 2026 · PeptideMethods Editorial Team · 5 min read