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Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.

Page 31

Explainer

What is GEP44? A GLP-1/PYY explainer

GEP44 is an investigational peptide that pairs GLP-1 with peptide YY signalling to test whether weight loss can come with fewer GI side effects.

17 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

GLP-1 agonists and throat symptoms

A study of 617,000 patients found GLP-1 agonists are linked to cough, throat discomfort, and voice changes. Here is what the evidence shows and why.

17 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

GLP-1 drugs in longevity medicine: 2026

A 2026 review examines what AOMs like semaglutide and tirzepatide have demonstrated in longevity medicine, and where the evidence is still preliminary.

17 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

How chemists test what's in GLP-1 drugs

A new peer-reviewed method identifies nine GLP-1 drugs at once. Here is why that kind of identity testing matters right now.

17 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

GHK-Cu + BPC-157: reconstitution guide

How to reconstitute GHK-Cu and BPC-157, whether combining them in one vial is advisable, and how to calculate doses when concentrations differ.

17 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

LC-HRMS screens 9 GLP-1 agonists at once

A 2026 Hong Kong study validated a single LC-HRMS method covering nine GLP-1 receptor agonists, from approved drugs to investigational compounds.

17 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Sports medicine peptides: the 2026 evidence

A 2026 UCLA scoping review found that the claimed benefits of BPC-157, TB-500, CJC-1295, MK-677, ipamorelin and GHK-Cu remain unsubstantiated by human trials.

17 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Retatrutide and gallbladder disease risk

Retatrutide is an investigational GLP-1, GIP and glucagon triple agonist. Here is what the trial and label data show about gallbladder risk.

17 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Obesity-driven HFpEF: the 2026 review

A 2026 systematic review maps how obesity drives HFpEF and frames SUMMIT trial data on tirzepatide into a practical clinical treatment approach.

17 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

COMBINE 4: IcoSema vs insulin glargine

COMBINE 4 put once-weekly IcoSema against daily insulin glargine U100 in type 2 diabetes. HbA1c fell further, and bodyweight moved the other way.

14 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Compounded tirzepatide with B6 explained

Compounded tirzepatide, including preparations with added vitamin B6, is not the licensed medicine. Here is what is documented and what is not.

14 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

How GLP-1 weight loss drugs really differ

Novo's CEO says patients want optionality. Here is what the approved labels and the single head-to-head trial say really separates these drugs.

14 Aug 2026 · PeptideMethods Editorial Team · 5 min read