#Incretin mimetics
GLP-1, GIP, glucagon receptor agonists.
New Model Explains Tirzepatide's Edge
A modeling study traces tirzepatide's fasting-glucose advantage over semaglutide to greater liver glucose suppression, not beta cells or extra weight loss.
MASLD Screening Without a Liver Biopsy
A new review explains how FIB-4 screens for MASLD and MASH in primary care, now that semaglutide and resmetirom can treat confirmed cases.
Why semaglutide alone beat the CRV431 combo
In a mouse model of advanced liver disease, semaglutide alone reduced tumor burden more than adding the investigational compound CRV431.
Tirzepatide and eyelid styes: what's known
A two-patient case series reports recurring eyelid styes and chalazia after tirzepatide, with one positive rechallenge.
GLP-1 Drugs and Lumbar Fusion Surgery
A new meta-analysis found no significant link between GLP-1 drugs like semaglutide and complications after lumbar fusion surgery.
Semaglutide After Pancreatitis: A Case
A new case report describes semaglutide controlling refractory hypertriglyceridemia after six pancreatitis episodes.
Obesity care outside trials
A new review examines how access, tolerability, persistence, and support can shape anti-obesity treatment outcomes in routine care.
GLP-1 use before bariatric surgery
A matched retrospective study linked prior GLP-1RA or tirzepatide use to lower recorded early cardiorenal events after bariatric surgery.
Semaglutide ASCVD cost model
A US veteran model found lifetime semaglutide added 1.31 QALYs but cost $118,996 per QALY at an assumed $14,000 annual price.
Tirzepatide and Work: Survey Findings
A survey of 518 US employees starting tirzepatide found strong support for obesity-drug coverage, but it did not measure treatment effects.
Tirzepatide and Exercise Anaphylaxis
A case report links tirzepatide with exercise-induced anaphylaxis in one patient, with no recurrence after the medicine was stopped.
How GLP-1 Analogs Are Engineered
A 2026 review explains how GLP-1 analogs use sequence changes, peptide shape and lipidation to resist breakdown and last longer.