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#FAQ
Reader-question driven format.
Explainer
Does Semaglutide cause muscle loss?
Semaglutide is associated with lean-mass loss, but around one-third of weight lost is lean tissue. Context from STEP 1 and two 2026 meta-analyses.
Explainer
Is semaglutide safe during pregnancy?
Semaglutide is contraindicated during pregnancy. The FDA label cites adverse fetal outcomes in animal studies; all phase 3 programmes excluded pregnant women.
Explainer
What happens after you stop retatrutide?
Retatrutide has no withdrawal trial yet, so here is what the semaglutide and tirzepatide discontinuation data suggest about stopping.