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#FAQ

Reader-question driven format.

Explainer

What a high IGF-1 result means

A high or high-normal IGF-1 result does not make tesamorelin safer. Here is what the label, human trials, and evidence gaps actually say.

7 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Can I buy tirzepatide online legally?

Tirzepatide is prescription-only in the EU, UK and US, so a legal online purchase means a licensed pharmacy dispensing against a valid prescription.

5 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Does tirzepatide cause muscle loss?

Tirzepatide causes some lean mass loss. DXA data from SURMOUNT-1 show roughly 75% of weight lost is fat and 25% is lean mass.

5 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Tirzepatide pregnancy: what the label says

The Mounjaro prescribing label flags insufficient human data and animal fetal harm. Here is what the label, animal studies, and early cohort data say.

5 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Can I buy semaglutide online legally?

Semaglutide is a prescription-only medicine in the US, UK and EU, so buying it online legally means a licensed pharmacy that requires a valid prescription.

31 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Can you drink alcohol on semaglutide?

Semaglutide's label carries no alcohol warning, but it flags gut, blood-sugar and pancreatitis effects that overlap with drinking. Here is the honest read.

31 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Does retatrutide cause muscle loss?

Retatrutide drives large weight loss, and some of it is lean mass. Here is what the one body-composition study and the wider GLP-1 evidence show.

31 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Does semaglutide cause muscle loss?

Semaglutide drives large weight loss, and some of it is lean mass. Here is what the body-composition data and the wider GLP-1 evidence show.

31 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Is semaglutide safe during pregnancy?

Semaglutide is not recommended in pregnancy. Here is what the Ozempic and Wegovy labels, the animal data, and the human exposure studies actually show.

31 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Is retatrutide safe during pregnancy?

Retatrutide is investigational with no approved label. Every trial excluded pregnant women. Here is what the class-level evidence and trial record show.

31 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Can you drink alcohol on retatrutide?

Retatrutide has no approved label, so there is no official alcohol guidance. Here is what the class literature and trial protocols report.

31 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Can I buy Semaglutide online legally?

Semaglutide is prescription-only in the US, UK, and EU. This explainer covers the legal routes by jurisdiction and the risks of grey-market supply.

31 Jul 2026 · PeptideMethods Editorial Team · 4 min read