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Explainer

Evidence-led entry points for non-clinicians. What is a GLP-1 receptor agonist, what does ATC A10BX mean, why are some peptides legal in Russia but not the EU.

Explainer

PT-141: reconstituting part of a vial

Vyleesi is a pre-filled autoinjector, not a powder. Research-grade PT-141 cakes are not evenly distributed, so splitting gives an unknown concentration.

5 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Selank headaches: what the research shows

Some users report headaches when starting Selank. Here is what the published research says about the peptide's neurotransmitter effects.

5 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

How semaglutide works: the GLP-1 receptor

Semaglutide binds the GLP-1 receptor in the pancreas, brain, and gut. Here is what happens at each site.

5 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Semaglutide side effects: what trials show

The STEP and SUSTAIN programmes documented semaglutide adverse events at scale. Here is what the data show, from GI effects to the thyroid boxed warning.

5 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Semaglutide WADA status

Semaglutide is not on the WADA prohibited list and requires no TUE. WADA is monitoring GLP-1 agonists. Here is what competing athletes need to know.

5 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

What is Semaglutide?

Semaglutide (Ozempic, Wegovy, Rybelsus) is a GLP-1 receptor agonist for type 2 diabetes and weight management. How it works and what the trials show.

5 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Semax dosing: what the trials used

Published Semax doses come from Russian stroke trials. No Western-standard human trial has validated any dose for other indications.

5 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Semax: from 1991 lab bench to today

Semax is licensed in Russia for stroke recovery but unapproved in the West. Here is how it got from a Moscow lab in 1991 to today's grey market.

5 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

How Semax works: mechanism explained

Semax is a seven-amino-acid ACTH fragment that reaches the brain intranasally and elevates BDNF. Here is what the data actually show.

5 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Semax side effects: what the trials report

Semax has no approved label outside Russia. Here is what the Russian clinical record and preclinical studies actually report on adverse effects.

5 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Can you mix peptides in one syringe?

No published compatibility data covers mixing KPV, GHK-Cu, tesamorelin, and ipamorelin in one syringe. Here is what formulation science shows.

3 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Sex differences in semaglutide muscle loss

A July 2026 study finds female ob/ob mice are protected from semaglutide-induced muscle loss while males are not. What the finding means and what it does not.

3 Jul 2026 · PeptideMethods Editorial Team · 4 min read