Explainer
Evidence-led entry points for non-clinicians. What is a GLP-1 receptor agonist, what does ATC A10BX mean, why are some peptides legal in Russia but not the EU.
Eli Lilly wins over Noom GLP-1 dose claims
The NAD recommended Noom drop its 'A Smaller Dose. A Smarter Start' tagline after Eli Lilly challenged the claim as unsupported by evidence.
GLP-1 drugs and lipedema: early evidence
A 2026 Dermatologic Surgery review found only two studies of GLP-1 receptor agonists in lipedema. The rationale is real, but the clinical evidence is thin.
Semaglutide in type 1 diabetes: Danish data
Danish registry data on 879 people with T1D who started semaglutide: HbA1c fell 0.52%, with no rise in hypoglycaemia or DKA hospitalisations.
Tirzepatide in Japan: real-world T2D data
A 324-patient Japanese study found tirzepatide cut HbA1c by 0.9 points and weight by 2.0 kg in 24 weeks of routine care.
Mounjaro and Zepbound: same drug, different names. Here is why
Mounjaro and Zepbound are both Eli Lilly's tirzepatide. Same molecule, same doses, different brands sold for different indications. The marketing split is regulatory, not pharmacological.