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Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.
Page 89
Semaglutide in type 1 diabetes: Danish data
Danish registry data on 879 people with T1D who started semaglutide: HbA1c fell 0.52%, with no rise in hypoglycaemia or DKA hospitalisations.
Tirzepatide in Japan: real-world T2D data
A 324-patient Japanese study found tirzepatide cut HbA1c by 0.9 points and weight by 2.0 kg in 24 weeks of routine care.
EMA backs extending Mounjaro to children with type-2 diabetes
On 11 December 2025 the EMA's CHMP recommended extending Mounjaro's licensed indication to adolescents and children aged 10 and over with insufficiently controlled type-2 diabetes.
Mounjaro and Zepbound: same drug, different names. Here is why
Mounjaro and Zepbound are both Eli Lilly's tirzepatide. Same molecule, same doses, different brands sold for different indications. The marketing split is regulatory, not pharmacological.
What Penn Medicine's 'food noise' case study actually showed
Casey Halpern's Nature Medicine case study recorded nucleus-accumbens activity in a single patient on tirzepatide. Activity was suppressed early, then returned at 5 months alongside renewed cravings.
Tirzepatide in the UK: how NICE TA924 and TA1026 shape access
Two NICE technology appraisals decide who gets Mounjaro on the NHS and under what criteria. TA924 covers type-2 diabetes; TA1026 covers obesity. They do not overlap.
TRIUMPH-1: retatrutide hits 28.3% weight loss at 80 weeks
Eli Lilly's first general-obesity Phase 3 readout for retatrutide: 28.3% mean body-weight reduction at 80 weeks on 12 mg weekly. Larger than any SURMOUNT-5 figure to date.