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Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.

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Explainer

Tirzepatide and kidney function in obesity

A 36-person real-world study found three months of tirzepatide improved eGFR in adults with obesity, with BMI change explaining about 19% of the kidney benefit.

18 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Tirzepatide and platelet volume in obesity

A 60-person retrospective study found tirzepatide reduced mean platelet volume 0.94 fL with a 3.92 BMI-unit drop. What the data shows and where it falls short.

18 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Tirzepatide vs GLP-1 agonists: MACE in T2D

A July 2026 JAHA study found tirzepatide linked to 25% lower MACE risk versus GLP-1 agonists in 16,402 matched patients with type-2 diabetes and ASCVD.

18 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Country deep-dive

Retatrutide in Sweden: no approval yet

Retatrutide holds no EMA or Läkemedelsverket authorisation as of July 2026. Here is where the TRIUMPH trials stand and what that means for Swedish patients.

17 Jul 2026 · PeptideMethods Editorial Team · 6 min read
Country deep-dive

Semax in Sweden: regulatory status

Semax has no marketing authorisation in Sweden or the EU. Here is the Läkemedelslagen framework, what changed in 2025-2026, and who to ask.

17 Jul 2026 · PeptideMethods Editorial Team · 6 min read
Explainer

Tesamorelin vs CJC-1295 with Ipamorelin

Both stacks pair a GHRH analog with ipamorelin, but tesamorelin and CJC-1295 have different half-lives and very different evidence bases.

16 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Semaglutide in Pakistan: real-world data

A 30-week Pakistan study reports HbA1c reductions of 1.86 points and 7.84 kg mean weight loss with semaglutide in routine outpatient care.

15 Jul 2026 · PeptideMethods Editorial Team · 3 min read
Explainer

Crunchometer: open-source feeding analysis

An open-source acoustic device for mice detects semaglutide appetite suppression and maps meal-tracking neurons in the lateral hypothalamus.

15 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 vs oral agents: insulin stop in T2D

A 2026 Annals study found GLP-1 agonists did not raise insulin discontinuation rates above SGLT-2 or DPP-4 inhibitors in 8,869 veterans with type 2 diabetes.

15 Jul 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 cancer risk vs bariatric surgery

A July 2026 study found GLP-1 receptor agonists were tied to lower colorectal and pancreatic cancer rates than bariatric surgery, not higher.

15 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

CRAVE study: GLP-1, food cravings, and diet

The CRAVE study tracked 28 adults on GLP-1 agonists for 24 weeks. Weight fell, diet quality did not improve, and micronutrient intake dropped.

15 Jul 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

How muscarine weakens heart contractions

Muscarine reduces cardiac contractile force in human atrial tissue only when cAMP is already elevated, including by GLP-1 agonists like semaglutide.

15 Jul 2026 · PeptideMethods Editorial Team · 4 min read