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Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.

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Expert digest

BPC-157 in Q3 2026: the FDA panel vote

The FDA's compounding panel voted 8 to 6 in July 2026 to back BPC-157 for the 503A bulks list, overruling its own reviewers. The evidence did not move.

2 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 and GIP: a short incretin history

Incretins went from a failed 1906 diabetes experiment to GLP-1 and GIP drugs. Here are the dates, the discoveries, and where the evidence thins out.

2 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 safety in neuroendocrine tumours

A 2026 European Journal of Endocrinology review weighs the evidence on GLP-1 receptor agonists like semaglutide in neuroendocrine neoplasms.

2 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Grey Market Semaglutide: Injection Errors

A 20-person study found untrained adults completed only 15 of 34 steps correctly when preparing grey market semaglutide from internet instructions.

2 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

MASLD and cardiovascular risk explained

MASLD affects 38% of adults worldwide and heart disease kills more of them than liver failure. Where semaglutide fits, and what remains unproven.

2 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Semaglutide and the septic rat heart

A 2026 rat study reports semaglutide limited sepsis-related heart injury by suppressing ferroptosis. There is no human data behind it.

2 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Tirzepatide and a rash: one case report

A 2026 JAAD case report links a year of tirzepatide to a widespread rash that cleared when the drug stopped. One patient is not a risk rate.

2 Aug 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Tirzepatide: 17% weight loss in real care

A 107-patient Spanish cohort reports 17.21% mean weight loss on tirzepatide at six months, at a median 7.5 mg dose. There is no control arm.

2 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Why weight loss stalls on tirzepatide

A weight loss plateau is the expected shape of the tirzepatide curve, not a failure. Here is what the trials show and where retatrutide really stands.

2 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

BPC-157, gentamicin and the rat kidney

A 2026 Zagreb rat study says BPC-157 blunted gentamicin kidney damage. Here is what a rodent nephrotoxicity result can and cannot tell a human reader.

1 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Does the eGFR dip explain heart benefit?

A 376-patient Saudi cohort asked whether the early eGFR change explains heart outcomes on dapagliflozin plus semaglutide. The answer was no.

1 Aug 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

GLP-1 timing and pregnancy blood pressure

A 2026 meta-analysis of three cohorts found no significant link between GLP-1 use around conception and hypertensive disorders of pregnancy.

1 Aug 2026 · PeptideMethods Editorial Team · 5 min read