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Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.

Page 19

Explainer

Mwyngil's non-GLP-1 obesity approach

Mwyngil is pursuing GPR75 and NLRP3 pathways for obesity. The targets are interesting, but the program remains preclinical.

9 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

How to read an oral GLP-1 script tracker

A new tracker follows oral Wegovy and Foundayo prescriptions. Here is what script growth can show, and what it cannot.

9 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

PT-141 microdosing: what the label says

Daily sub-label PT-141 schedules sit outside the Vyleesi label and well below the lowest dose ever taken into a published controlled trial.

9 Sept 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

T-BEAT Japan: design, not results

The T-BEAT paper describes a Japanese tirzepatide and oral semaglutide study, but reports baseline data rather than treatment outcomes.

9 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Tirzepatide and SGLT2 drugs in HFpEF

A 2026 review sets tirzepatide against the SGLT2 inhibitors in obesity-related HFpEF. The mechanisms look complementary. No trial has tested them together.

9 Sept 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

MASH screening in type 2 diabetes

A new model finds staged, non-invasive MASH screening cost-effective for adults with type 2 diabetes across six countries.

8 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Melanotan 1: why the tan comes out patchy

Melanotan 1 triggers melanin in all skin, not just sun-exposed surfaces, which explains tiger-stripe pigmentation in people with loose or aged skin.

8 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

A semaglutide case report on dysautonomia

A 2026 case report described symptom improvement after semaglutide in one patient with dysautonomia. It does not establish a treatment.

8 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Semaglutide and endothelial markers

A post hoc randomized-trial analysis found mixed endothelial marker results after 32 weeks of semaglutide in type 2 diabetes.

8 Sept 2026 · PeptideMethods Editorial Team · 5 min read
Expert digest

TB-500 in 2026 Q2: what changed

Q2 2026 gave TB-500 an FDA compounding review date and one new thymosin beta 4 heart trial, while the injury recovery evidence stayed still.

8 Sept 2026 · PeptideMethods Editorial Team · 5 min read
Expert digest

Tesamorelin in 2026 Q2: what changed

Q2 2026 gave tesamorelin one null cognition pilot and three reviews. Its FDA label, its EU status and its trial pipeline all stayed put.

8 Sept 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Does tirzepatide cut carpal tunnel risk?

A 2026 cohort study links tirzepatide to fewer carpal tunnel diagnoses than other weight drugs. That is an association, not a treatment effect.

8 Sept 2026 · PeptideMethods Editorial Team · 5 min read