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Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.

Page 19

Explainer

HISTORI Semaglutide Record: What We Know

A PubMed record describes a semaglutide trial in schizophrenia, prediabetes, and obesity, but currently supplies no abstract or outcome data.

22 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

MASH combination therapy: review insights

A 2026 review explains why MASH combination therapy is being explored, while leaving major questions unresolved.

22 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

MASH eligibility tests: study findings

A multicentre cohort found that proposed non-invasive MASH eligibility criteria classified many patients differently.

22 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Retatrutide and gut-health claims

A podcast discussion can raise useful questions, but phase 2 retatrutide evidence does not make it an approved general tool for gut health.

22 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

STEP UP semaglutide muscle findings

A small STEP UP MRI subgroup found lower thigh fat infiltration and lower measured muscle volume, with sit-to-stand repetitions preserved.

22 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Comparison

BPC-157 vs TB-500 for injury recovery

BPC-157 has more injury-specific animal research than TB-500, but neither has solid human evidence for faster recovery.

21 Sept 2026 · PeptideMethods Editorial Team · 5 min read
Comparison

Ipamorelin vs CJC-1295: GH-axis stack

Ipamorelin and CJC-1295 act on different GH pathways, but no human trial has shown that combining them improves clinical outcomes.

21 Sept 2026 · PeptideMethods Editorial Team · 6 min read
Explainer

The science behind nose-to-brain peptides

Semax, Selank and oxytocin sprays can reach the brain via the olfactory nerve, but not through any special breathing or injection trick.

21 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Trial readouts

What 49 Online GLP-1 Prescribers Required

A secret-shopper study found rapid access to GLP-1 prescriptions across 49 US websites, often without direct clinician-patient communication.

21 Sept 2026 · PeptideMethods Editorial Team · 5 min read
Explainer

Oral Semaglutide and Cognitive Decline Risk

A small elderly-cohort study links oral semaglutide to less cognitive impairment than DPP-4 inhibitors, but a large Alzheimer's trial found no benefit.

21 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Semaglutide Patches Need a Different Needle

New research shows dissolving microneedle patches need different needle designs for semaglutide than for small drugs.

21 Sept 2026 · PeptideMethods Editorial Team · 4 min read
Explainer

Semaglutide Plus Niacin for Lung Fibrosis

A rat study paired semaglutide with niacin against lung scarring, targeting the NAD+/SIRT1-FOXO3a-Nrf2 pathway. Here is what it does and does not show.

21 Sept 2026 · PeptideMethods Editorial Team · 4 min read