Blog
Daily evidence-led peptide research, regulatory news, expert digest and explainers. Every claim sourced; no AI tells.
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Is semaglutide safe during pregnancy?
Semaglutide is contraindicated during pregnancy. The FDA label cites adverse fetal outcomes in animal studies; all phase 3 programmes excluded pregnant women.
GH-axis peptides: weighing the evidence
Tesamorelin, CJC-1295 and ipamorelin sit on three different rungs of the evidence ladder. Here is how to weight what each one actually shows.
GH-axis peptides: grading the evidence
Tesamorelin has two Phase 3 RCTs and FDA approval. CJC-1295 has two early-phase studies. Ipamorelin has one PK study and a negative Phase 2.
Peptides for injury recovery: the evidence
BPC-157 and TB-500 are the most-asked injury-recovery peptides. Here is what is trial-supported, what is animal-only, and what is just anecdote.
Peptide longevity: what the evidence shows
What trial data supports for peptides marketed for longevity: from GLP-1 cardiovascular outcomes to preclinical Epitalon and GHK-Cu research.
Peptides for muscle gain: the evidence
Ipamorelin and CJC-1295 lead the muscle-gain peptide conversation. Here is how their evidence actually ranks, from human pharmacology to mouse data to anecdote.
Sexual-function peptides: the evidence
Only one sexual-function peptide, bremelanotide (Vyleesi), has real trial support, and only for one use. Here is how to weigh the evidence tier by tier.
Peptides for sleep: the evidence grade
MK-677 has a small controlled trial showing improved sleep architecture. Ipamorelin and CJC-1295 raise GH, but their sleep effects remain untested in humans.
Longevity peptides: weighing the evidence
Tesamorelin and ipamorelin get sold as anti-aging tools. Here is what the trial evidence actually supports, and the longevity gap it leaves.
What happens after you stop retatrutide?
Retatrutide has no withdrawal trial yet, so here is what the semaglutide and tirzepatide discontinuation data suggest about stopping.
What CJC-1295 actually costs in the US
CJC-1295 has no FDA approval and no legal US pharmacy price. Here is why the only figures you find are grey-market, and what that low number really signals.
Ipamorelin in the US: import rules
Ipamorelin is not FDA-approved. Importing an unapproved drug for personal use is illegal under US federal law, with narrow exceptions it does not meet.