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#Obesity medicine

Chronic weight management as a clinical specialty.

Explainer

Iran's GLP-1 Cost-Effectiveness Model

An Iranian 68-week model found semaglutide cost-effective at its threshold, while tirzepatide offered more benefit at a higher estimated cost.

20 Oct 2026 · PeptideMethods Editorial Team · 4 min read
Trial readouts

GLP-1 Drugs and AF in Obesity With CKD

A matched cohort linked GLP-1 receptor agonist use with less one-year atrial fibrillation in non-diabetic adults with obesity and CKD.

19 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

Tirzepatide and TLR2 Inflammation in Mice

A mouse and cell study found tirzepatide reduced selected inflammatory responses after a Western diet. It was not a clinical outcomes trial.

19 Oct 2026 · PeptideMethods Editorial Team · 4 min read
Trial readouts

GLP-1 Hair Loss Review: What It Found

A 2026 GLP-1 hair loss review links shedding mainly to weight change, but the narrative evidence cannot prove direct drug causation.

15 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

GLP-1 Drugs Cut Test-Meal Intake

A 2026 meta-analysis found GLP-1 therapy reduced intake by about 271 kcal at one test lunch, with real-world diet effects still uncertain.

15 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

Oral Semaglutide: 4-Month Study

A 70-person observational study linked four months of oral semaglutide care with lower weight, mostly through reduced fat mass.

15 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

Pediatric Obesity Drug Review: Gaps

A 2026 pediatric obesity drug review links adolescent semaglutide evidence with adult retatrutide research while leaving long-term safety open.

15 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

Adolescent GLP-1 Review: Evidence Gaps

A 2026 review finds short-term benefits from adolescent GLP-1 therapy but major gaps around growth, puberty, cognition and lifelong effects.

14 Oct 2026 · PeptideMethods Editorial Team · 4 min read
Trial readouts

Tirzepatide 2.5 vs 5 mg: Japanese cohort

A non-randomized Japanese cohort reported similar six-month weight loss with 2.5 mg and 5 mg tirzepatide, without proving dose equivalence.

14 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

Tirzepatide in Heart Failure: Review

A 2026 meta-analysis links tirzepatide to lower cardiorenal biomarkers, while functional and kidney findings remain based on single trials.

14 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

α-Lactalbumin nanomicelles in obese mice

A mouse study tested sulforaphene-loaded α-lactalbumin nanomicelles against semaglutide, but it provides no human efficacy or safety evidence.

13 Oct 2026 · PeptideMethods Editorial Team · 5 min read
Trial readouts

Australia GLP-1 access trends, 2020-2025

Australian sales and PBS data show rapid GLP-1 medicine growth, with nearly half of estimated use accessed privately in the final study year.

13 Oct 2026 · PeptideMethods Editorial Team · 5 min read