#GLP-1 class
Coverage of the GLP-1 receptor agonist family and its successors.
CagriSema pen usability: the study results
A 150-person study tested whether adults with overweight or diabetes could use the CagriSema dual-chamber autoinjector correctly after 3 minutes of training.
GLP-1 drugs in Medicaid: the coverage gap
Most US Medicaid programs restrict or exclude GLP-1 obesity drugs. Here is what the research says about who gets access and why coverage varies by state.
Health Canada vs FDA: approval paths
A 2026 JGIM study compares how Health Canada and the FDA use expedited pathways, with implications for Canadian patients waiting on GLP-1 approvals.
Semaglutide P29: a new production method
A 2026 PLoS ONE study reports 5.85 g/L yield and 98% purity for the semaglutide main-chain intermediate using a SNAC-tagged bacterial expression system.
Semaglutide and diabetes recovery stories
A 2026 medical humanities paper asks what happens to patient recovery narratives when semaglutide does much of the biological work.
Semaglutide and weight in schizophrenia
A 24-week trial found semaglutide reduced body weight by 9.8% in people with schizophrenia on clozapine or olanzapine, with partial regain after stopping.
GLP-1 drugs and mental health: a 2026 study
A June 2026 cohort study found lower rates of anxiety and depression in adults on tirzepatide or semaglutide vs other weight-loss drugs, and what that means.
Tirzepatide and steatotic liver disease
A 2026 real-world study finds tirzepatide cut major liver complications and mortality in adults with steatotic liver disease and cardiometabolic dysfunction.
GLP-1/GIPR/FGF21 peptibody in DIO mice
A preclinical peptibody hitting GLP-1, GIPR, and FGF21 reduced body weight and improved metabolic markers in obese mice. Human translation is unknown.
Semaglutide and the cost of CV benefit
A 2026 cost-effectiveness review places semaglutide, a GLP-1 agonist, in the moderate tier for preventing cardiovascular events. Here is what that means.
Semaglutide and heart risk: a 2026 review
A 2026 meta-analysis of 11 trials found semaglutide cut major cardiovascular events by about a third, similarly in people with and without diabetes.
Semaglutide for non-diabetic CKD: review
A 2026 review pooled 3 studies on semaglutide for non-diabetic obesity with kidney disease or hypertension. The signal is early, not long-term.