#GLP-1 class
Coverage of the GLP-1 receptor agonist family and its successors.
Tirzepatide and MASLD in Mice
A mouse and cell study linked tirzepatide with less liver fat and inflammation, with Dectin-1 signaling proposed as part of the mechanism.
GLP-1 safety cohort: what it found
A 2026 South Korean cohort linked semaglutide and liraglutide initiation with selected safety outcomes, without proving causation.
Personalising Tirzepatide Maintenance
A Lancet letter raises the maintenance question. SURMOUNT-MAINTAIN supports continued tirzepatide but does not supply an individual dosing formula.
Semaglutide equity model explained
A 25-year semaglutide model weighed cost per QALY against projected equity for older adults with obesity and cardiovascular disease.
Tirzepatide During ECT: One Case
One patient taking tirzepatide completed 17 ECT sessions without complications, but the case report cannot establish a safe protocol.
Tirzepatide and Migraine: Two Cases
Two patients reported fewer migraine days on tirzepatide, but weight loss and an uncontrolled design prevent causal conclusions.
Tirzepatide Ocular Study: What We Know
A letter on tirzepatide ocular outcomes has no public abstract. The underlying cohort found associations, not proof of eye protection.
Vutiglabridin and Semaglutide in Mice
A preclinical mouse study found more fat loss with vutiglabridin plus semaglutide, but it provides no evidence of human efficacy.
HD1916 trial: chemically made semaglutide
A Phase III trial found HD1916 met its prespecified equivalence criterion against reference semaglutide for weight change at 44 weeks.
Tirzepatide and oral symptoms
A 2026 paper describes reported oral and salivary symptoms with incretin medicines, but it does not establish causation for tirzepatide.
Tirzepatide vs SGLT2 Drugs in MASLD
A matched MASLD cohort linked tirzepatide to fewer deaths and liver events than SGLT2 inhibitors, but it cannot prove superiority.
GIP Agonists and Blockers in Obesity
A 2026 review asks why GIP receptor agonists and blockers can both support weight loss, then separates mouse mechanisms from human trial evidence.