#For patients
Written for adults considering a peptide as part of their health management.
GLP-1 Drugs and Kidney Fibrosis in Mice
A new mouse study compared semaglutide, tirzepatide and retatrutide on kidney fibrosis. Here is what the animal data does and does not show.
Semaglutide safety in dialysis patients
A 2026 Diabetes Care exchange scrutinised pooled trial data on semaglutide safety after dialysis initiation. What the numbers show and what remains open.
Can you freeze a reconstituted peptide?
A reader paused a CJC-1295/ipamorelin cycle and wanted to freeze the rest. Here is what the closest approved label and the freeze-thaw literature say.
Selank and Semax: Should You Combine Them?
Selank has real generalized anxiety disorder trial data. Semax's focus reputation does not, and no study has combined the two.
Tirzepatide vs Semaglutide: Liver Risk
A large real-world study found tirzepatide and injectable semaglutide carry the same risk of serious liver outcomes in adults with type 2 diabetes.
Switching to Tirzepatide: Liver Fibrosis
A Japanese study found switching from other GLP-1 drugs to tirzepatide reduced FIB-4 liver fibrosis scores in high-risk patients.
Avexitide: the GLP-1 drug that blocks it
Avexitide, Amylyx's investigational GLP-1 receptor blocker, cut severe post-bariatric hypoglycemia events by 55 percent in a phase 3 trial.
ENV-308: a pill built to mimic exercise
Enveda's ENV-308 mimics an exercise-linked metabolite and aims to preserve muscle after GLP-1 weight loss, but its Phase 1 trial tested only safety.
GLP-1 Drugs and Ankle Osteoarthritis Care
A 2026 cohort study ties GLP-1 receptor agonist use to fewer ankle injections and replacements, but more arthroscopy in diabetes.
Hunger pain: semaglutide in schizophrenia
A qualitative study asked people with schizophrenia how semaglutide changed the hunger antipsychotics can cause.
Sleep and mood after starting GLP-1 drugs
A new observational study links tirzepatide and semaglutide to improved sleep and depression scores at three months, with caveats.
Doctor suspended over Ozempic to partner
A GMC tribunal suspended a UK doctor for prescribing Ozempic and Wegovy, both semaglutide, to her partner without disclosure.