Explainer
Evidence-led entry points for non-clinicians. What is a GLP-1 receptor agonist, what does ATC A10BX mean, why are some peptides legal in Russia but not the EU.
Semaglutide Before Surgery: What to Ask
Semaglutide can affect stomach emptying before anesthesia. Your surgical and prescribing teams need the full medication history, symptoms, and dose changes.
A semaglutide accomplishment in context
A Wegovy user's story about kneeling comfortably again is meaningful, but a community post cannot establish a treatment effect for others.
Semaglutide weight-loss timelines explained
Semaglutide trial averages can set context, but they cannot predict how much weight one person will lose or when.
HIV Weight Gain and Semaglutide
HIV-associated weight gain can involve visceral fat. Here is what a small semaglutide trial found, and what it cannot answer.
Semaglutide and frailty: what we know
A new JAMA report raises questions about semaglutide across frailty levels. Here is what its headline can and cannot establish.
Can Anti-Doping Tests Detect Semaglutide?
A 2026 study describes a urine method for detecting markers of oral semaglutide exposure, with important limits on what it can show.
GLP-1 Receptor Agonists in Psoriasis
Research on GLP-1 receptor agonists in psoriasis is promising but limited. Here is what current reviews and a recent trial do and do not show.
GLP-1 drugs and the ocular surface
A 2026 review links GLP-1 drugs to possible ocular-surface repair and changes around the eye, but human evidence remains small and observational.
GLP-1 Drugs and OSA Complication Risk
A five-year database study linked GLP-1 drugs to fewer lung complications in people with sleep apnea and type 2 diabetes, without proving causation.
GLP-1 drugs and sleep apnea outcomes
A matched US database study links GLP-1 drug use in sleep apnea with fewer strokes, hospital visits and deaths, but it cannot prove cause and effect.
Retatrutide Results and the 25% Finding
A phase 3 retatrutide trial reported mean body-weight change of 25.0% at 80 weeks in one study group. Here is what that result does and does not show.
Peptides before shoulder replacement
What human evidence and surgical guidance can say about TB-500, BPC-157, and other peptides before shoulder replacement.